Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Publisher

Elsevier

Language

‎English

Edition

1st

Format

Publisher PDF

File Size

28.2 MB

ISBN-10

0470949457

ISBN-13

978-0470949450, 9780470949450

$27.00

5/5
Description

Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Retrometabolic Drug Design and Targeting introduces an innovative paradigm for drug design that holds promise for yielding viable drug products.

This novel approach encompasses two distinct strategies, geared toward the creation of soft drugs and the development of chemical delivery systems, respectively.

Merging theoretical foundations with pragmatic, step-by-step illustrations, this comprehensive work equips its readers with the essential tools to harness retrometabolic methodologies, thereby fostering the creation of targeted drug therapies that are both efficacious and secure.

Authored by luminaries in the fields of soft drugs and retrometabolic drug design, this seminal work presents a reservoir of insights, strategies, and remedies, catering to a spectrum of challenges intrinsic to drug design—ranging from optimization and stability to side effects and toxicity.

The inception of Retrometabolic Drug Design and Targeting commences with an inaugural chapter that delves into contemporary pharmaceutical advancements and the concomitant challenges within the ambit of modern drug discovery.

Subsequent chapters navigate the fundamental aspects of drug action mechanisms, the intricate trajectory of drug discovery and development, and the nuanced nuances of retrometabolic drug design.

The discussions traverse the realms of soft drugs and chemical delivery systems, expounding upon their underpinnings and practical applications.

Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Intrinsic to the narrative are exemplars culled from diverse pharmacological domains, meticulously elucidating the rationale behind each drug design endeavor.

These instances cogently outline the pertinent pharmacokinetic and pharmacodynamic attributes of the nascent therapeutic agents, cogently juxtaposing these attributes with those exhibited by other compounds harnessed for analogous therapeutic intentions.

Moreover, the authors extend their purview to dedicated computer programs, which serve to augment and streamline retrometabolic drug design endeavors.

Retrometabolic Drug Design and Targeting is a recommended companion for researchers vested in the realm of pharmaceutical innovation, catering to those who seek to harness the proven potential of this trailblazing methodology for the creation of drugs that seamlessly balance efficacy and safety.

This work stands as an embodiment of the evolution in drug design paradigms, poised to shape the landscape of pharmacotherapy by offering a framework that bridges theoretical innovation with tangible therapeutic outcomes.

 

1.2.Key Features

The preeminent key features of Retrometabolic Drug Design and Targeting converge to present an indispensable guide that heralds a paradigm shift in drug design, poised to redefine the landscape of pharmaceutical innovation. This remarkable work is characterized by the following salient attributes:

  1. Innovative Design Paradigm: Retrometabolic Drug Design and Targeting introduces an avant-garde approach that merges two distinct strategies—soft drugs and chemical delivery systems—enabling the creation of novel drug products with heightened efficacy and safety profiles.
  2. Comprehensive Approach: With an intricate interplay of theoretical foundations and practical exemplars, the book offers a comprehensive understanding of retrometabolic methodologies, rendering it a pivotal resource for navigating the multifaceted terrain of drug design.
  3. Pioneering Authorship: Authored by trailblazers in the fields of soft drugs and retrometabolic drug design, the book emanates from the expertise of luminaries, ensuring the delivery of authoritative insights, strategies, and solutions.
  4. Addressing Challenges: This work is adept at addressing a spectrum of challenges intrinsic to drug design, encompassing optimization, stability, side effects, and toxicity, thereby arming readers with innovative solutions that reconcile therapeutic efficacy with patient safety.
  5. Illustrative Exemplars: The inclusion of diverse pharmacological case studies serves to illustrate the rationale underpinning each drug design endeavor, offering a tangible link between theory and practical implementation.
  6. Pharmacokinetic and Pharmacodynamic Insight: The exemplars thoughtfully juxtapose the pharmacokinetic and pharmacodynamic attributes of newly designed therapeutic agents with existing compounds, providing a nuanced understanding of their potential impact.
  7. Integration of Technology: Retrometabolic Drug Design and Targeting delves into dedicated computer programs that bolster and streamline retrometabolic drug design efforts, incorporating cutting-edge technology for enhanced outcomes.
  8. Practical Applications: By bridging theoretical foundations with real-world applications, the book empowers researchers, practitioners, and scholars to harness retrometabolic approaches in their pursuit of safe and effective targeted drug therapies.
  9. Transformational Impact: Retrometabolic Drug Design and Targeting holds the potential to reshape the landscape of drug design, offering an innovative framework that optimizes therapeutic outcomes while minimizing associated risks.

In essence, Retrometabolic Drug Design and Targeting emerges as a beacon of transformative potential within the realm of drug design.

Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Retrometabolic Drug Design and Targeting

As it paves the way for a new era of pharmaceutical innovation, it equips professionals with the necessary tools to usher in a future characterized by groundbreaking drugs that revolutionize patient care and redefine the boundaries of medical possibility.

 

1.3. About Writers

Nicholas Bodor, Ph.D., and Peter Buchwald, Ph.D., stand as accomplished authors with remarkable contributions to the realm of pharmaceutical sciences.

Dr. Bodor, a distinguished researcher, holds a prominent place in the field of drug design and delivery. His pioneering work encompasses novel drug delivery systems and prodrug concepts, fostering advancements in drug targeting and bioavailability.

Dr. Buchwald, equally esteemed, has made significant strides in medicinal chemistry, particularly in the areas of drug synthesis and structure-activity relationships.

With an extensive academic background, they jointly co-authored notable works, exemplifying their expertise in the convergence of theoretical pharmacology and practical applications.

Their achievements extend to pioneering advancements in retrometabolic drug design, offering transformative insights and strategies that are poised to revolutionize targeted drug therapies.

Through their collective scholarly endeavors, Dr. Bodor and Dr. Buchwald have left an enduring impact on the pharmaceutical landscape, reshaping drug design paradigms and enhancing the frontiers of pharmacological innovation.

Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Retrometabolic Drug Design and Targeting (Original PDF from Publisher)

Summary

Retrometabolic Drug Design and Targeting presents a pioneering approach to drug design, expertly curated by Nicholas Bodor, PhD, and Peter Buchwald, PhD. This innovative work seamlessly combines two distinctive strategies, soft drugs and chemical delivery systems, to usher in a new era of pharmaceutical advancement.

By weaving theoretical principles with practical case studies, the book equips readers with the tools to harness retrometabolic methodologies for the creation of safe and effective targeted drug therapies.

Authored by luminaries in the fields of drug design and medicinal chemistry, this comprehensive guide addresses challenges in drug optimization, stability, side effects, and toxicity.

With a focus on transformative solutions and integration of cutting-edge technology, this book emerges as a cornerstone for researchers, professionals, and students seeking to pioneer the next generation of pharmaceutical innovations.

 

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Categories:

Medical Sciences and Research 

Pharmacology 

 

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